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It belongs to the family of medications known as opioid analgesics. In particular, U47700 is an opioid that is classified under the benzamide umbrella. It is not utilized in medicine but rather in research for scientific purposes.
U-47700 is referred to by its systematic name, 3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide, as well as its official IUPAC designation. The empirical chemical formula for it is C16H22Cl2N2O, and its molar mass is 329.27 grams in total weight.
In the late 1970s, a group of researchers working for the pharmaceutical company Upjohn was the first to come up with the concept.
It was found that U47700 had a potency that was 7.5 times higher than that of the traditional therapeutic opiate morphine when tested on animal models.
U47700 has a far lower binding relationship at the kappa opioid receptor than it does at the -opioid receptor, where it has a Kd value of 910 nM. From a pharmacological standpoint, U47700 is a selective agonist at the -opioid receptor, where its Kd value is 5.3 nM.
An older opioid called AH-7921 is the opioid that U47700 is a structural counterpart of.
This substance is unfit for eating by either human beings or animals.
Although they are subjective and unverifiable, reports found online do point to a number of traits possessed by this substance.
It has been claimed that taking U-47700 may result in sensations of exhilaration, as well as relief from pain and suppression of anxiety. Some users have reported experiencing symptoms that are akin to those caused by the prescription oxycodone, which is extensively misused.
The feeling of euphoria is said to be milder in contrast to that produced by morphine or heroin. The sensation that is created is said to be one of “warmth” and “comfort” that travels throughout the body.
It has been claimed that the sedative effects of U47700 are substantially more profound than those of similar opiates such as oxycodone or hydrocodone.
A decrease in libido, constriction of the pupils, trouble urinating, suppression of coughing, and constipation are some of the other effects of this drug. This is consistent with the typical negative effects that opiates have on the body.
Because it causes histamine to be released, U47700 may cause the skin to become very itchy.
It is important to be aware that respiratory depression is a common adverse effect of opioids and is the primary factor in the toxicity of these substances. In spite of the fact that there have been no systematically conducted investigations on the physiological effects of U47700 on people, anecdotal accounts indicate that U47700 has a tendency to generate far greater respiratory depression than heroin or morphine. Because of this, U47700 is a very hazardous substance, and users should approach it with the utmost care. It has been observed that U47700, when taken in low quantities, causes a slight slowing of the breath but does not induce a highly obvious impairment. Higher dosages and overdoses have the effect of incapacitating the user, as shown by reports of irregular breathing patterns, a lack of air, and loss of consciousness. This may rapidly result in irreversible brain damage, which can be deadly.
U47700, like other opioids, is known to generate a multitude of unpleasant aftereffects collectively referred to as the “crash.” Among them include feelings of agitation, impatience, negative emotional states, cognitive tiredness, difficulties thinking, anxiety, sadness, and a lack of desire.
Because of its very high potency in contrast to other types of opioids and opiates, U-47700 has a significant toxicity that is proportional to the dosage. Because of this, it is not a good recreational chemical and there is a substantial danger that the user will be harmed by it. As a result, extreme care has to be used with regard to the dosage. The lethality of the molecule is further increased when it is combined with other depressants like alcohol, benzodiazepines, GHB/GBL, and dissociatives like ketamine. This is because all of these substances slow down the central nervous system. U-47700 Online
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